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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2001-12-13
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pubmed:databankReference |
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pubmed:abstractText |
The DNA sequence of a 7.8-kb Helicobacter pylori plasmid, pHPM8, was determined. Six open reading frames (ORFs) were present. Ribonuclease protection studies showed that ORF1/ORF2 and ORF3/ORF4 genes are organized in operons possibly involved in plasmid replication and in production of a peptide with antibiotic activity, respectively. Finding areas of pHPM8 with a high level of identity to H. pylori chromosomal DNA supported the hypothesis that recombination occurs between plasmids and the chromosome of H. pylori.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0147-619X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 Elsevier Science.
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11735371-Amino Acid Sequence,
pubmed-meshheading:11735371-Bacterial Proteins,
pubmed-meshheading:11735371-Chromosomes, Bacterial,
pubmed-meshheading:11735371-DNA, Bacterial,
pubmed-meshheading:11735371-DNA Replication,
pubmed-meshheading:11735371-Drug Resistance,
pubmed-meshheading:11735371-Gene Expression Regulation, Bacterial,
pubmed-meshheading:11735371-Genes, Bacterial,
pubmed-meshheading:11735371-Genes, Overlapping,
pubmed-meshheading:11735371-Helicobacter pylori,
pubmed-meshheading:11735371-Molecular Sequence Data,
pubmed-meshheading:11735371-Open Reading Frames,
pubmed-meshheading:11735371-Operon,
pubmed-meshheading:11735371-Plasmids,
pubmed-meshheading:11735371-Sequence Alignment,
pubmed-meshheading:11735371-Sequence Homology, Amino Acid
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pubmed:year |
2001
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pubmed:articleTitle |
Sequence and gene expression analyses of plasmid pHPM8 from Helicobacter pylori reveal the presence of two operons with putative roles in plasmid replication and antibiotic activity.
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pubmed:affiliation |
Biology Department, Texas Woman's University, Denton, Texas 76204, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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