Source:http://linkedlifedata.com/resource/pubmed/id/11731664
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2001-12-3
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pubmed:abstractText |
The religious convictions of parents who are Jehovah's Witness adherents lead them to reject the use of exchange transfusions as therapy for severe hyperbilirubinemia in newborns in whom intensive phototherapy has failed to control this problem. Consequently, physicians caring for such infants may be obliged to initiate legal action to compel use of the procedure when severe hyperbilirubinemia not sufficiently responsive to phototherapy warrants an exchange transfusion. Our goal was to determine if we could use the potent inhibitor of bilirubin production, Sn-Mesoporphyrin (SnMP), to resolve the troubling medical-legal issues in such situations in 2 infants with hemolytic disease of the newborn who required exchange transfusions for severe hyperbilirubinemia but whose Jehovah's Witness parents rejected the procedure. SnMP was administered in a single dose, as in previous studies, at the time when exchange transfusion would have been initiated and plasma bilirubin levels were monitored at close intervals thereafter.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Bilirubin,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Heme Oxygenase (Decyclizing),
http://linkedlifedata.com/resource/pubmed/chemical/Metalloporphyrins,
http://linkedlifedata.com/resource/pubmed/chemical/tin mesoporphyrin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1098-4275
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1374-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11731664-Bilirubin,
pubmed-meshheading:11731664-Blood Transfusion,
pubmed-meshheading:11731664-Christianity,
pubmed-meshheading:11731664-Enzyme Inhibitors,
pubmed-meshheading:11731664-Erythroblastosis, Fetal,
pubmed-meshheading:11731664-Female,
pubmed-meshheading:11731664-Heme Oxygenase (Decyclizing),
pubmed-meshheading:11731664-Humans,
pubmed-meshheading:11731664-Hyperbilirubinemia,
pubmed-meshheading:11731664-Infant, Newborn,
pubmed-meshheading:11731664-Infant, Premature,
pubmed-meshheading:11731664-Male,
pubmed-meshheading:11731664-Metalloporphyrins,
pubmed-meshheading:11731664-Religion and Medicine
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pubmed:year |
2001
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pubmed:articleTitle |
Sn-Mesoporphyrin interdiction of severe hyperbilirubinemia in Jehovah's Witness newborns as an alternative to exchange transfusion.
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pubmed:affiliation |
Rockefeller University, New York, NY 10021, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
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