Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-11-30
pubmed:abstractText
Reflux of duodenal contents including bile acids is believed to contribute to esophageal injury and Barrett's esophagus. Cyclooxygenase (COX)-2, an inducible form of COX, has been implicated in both inflammation and carcinogenesis. In this study, we investigated the effects of bile acids and duodenal reflux on COX-2 expression in cultured esophageal cells and tissue, respectively.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
121
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1391-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:11729118-Animals, pubmed-meshheading:11729118-Bile Acids and Salts, pubmed-meshheading:11729118-Chenodeoxycholic Acid, pubmed-meshheading:11729118-Cyclooxygenase 2, pubmed-meshheading:11729118-Duodenogastric Reflux, pubmed-meshheading:11729118-Enzyme Induction, pubmed-meshheading:11729118-Esophagus, pubmed-meshheading:11729118-Gastroesophageal Reflux, pubmed-meshheading:11729118-Glycochenodeoxycholic Acid, pubmed-meshheading:11729118-Isoenzymes, pubmed-meshheading:11729118-Male, pubmed-meshheading:11729118-Mucous Membrane, pubmed-meshheading:11729118-Phosphatidylinositol 3-Kinases, pubmed-meshheading:11729118-Prostaglandin-Endoperoxide Synthases, pubmed-meshheading:11729118-Prostaglandins, pubmed-meshheading:11729118-Rats, pubmed-meshheading:11729118-Rats, Sprague-Dawley, pubmed-meshheading:11729118-Signal Transduction, pubmed-meshheading:11729118-Tumor Cells, Cultured
pubmed:year
2001
pubmed:articleTitle
Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids.
pubmed:affiliation
Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't