|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
22
|
|
pubmed:dateCreated |
2001-11-21
|
|
pubmed:abstractText |
Interleukin 15 (IL-15) activates cytotoxic lymphocytes and drives the expansion of memory T cells. Its role in immune control of virus-transformed cells and other tumor cells remains to be elucidated. We investigated the role of IL-15 in controlling Epstein-Barr virus (EBV)-transformed/immortalized lymphocytes in culture. EBV is a highly potent lymphocyte-transforming and opportunistic oncogenic herpesvirus associated with several human tumors.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0027-8874
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
21
|
|
pubmed:volume |
93
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1724-32
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:11717333-B-Lymphocytes,
pubmed-meshheading:11717333-Cell Division,
pubmed-meshheading:11717333-Cell Line, Transformed,
pubmed-meshheading:11717333-Cell Transformation, Viral,
pubmed-meshheading:11717333-Cells, Cultured,
pubmed-meshheading:11717333-Cytotoxicity, Immunologic,
pubmed-meshheading:11717333-Epstein-Barr Virus Nuclear Antigens,
pubmed-meshheading:11717333-Herpesvirus 4, Human,
pubmed-meshheading:11717333-Humans,
pubmed-meshheading:11717333-Interleukin-15,
pubmed-meshheading:11717333-Killer Cells, Natural,
pubmed-meshheading:11717333-Lymphocyte Activation,
pubmed-meshheading:11717333-Lymphocyte Subsets,
pubmed-meshheading:11717333-Recombinant Proteins,
pubmed-meshheading:11717333-T-Lymphocytes,
pubmed-meshheading:11717333-Time Factors
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Interleukin 15-mediated induction of cytotoxic effector cells capable of eliminating Epstein-Barr virus-transformed/immortalized lymphocytes in culture.
|
|
pubmed:affiliation |
Laboratory of Immunovirology, Department of Microbiology and Immunology, and Pediatric Research Center, University of Montreal and Sainte-Justine Hospital, Montreal, PQ, Canada.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
