Linked Life Data

11711901

Source:http://linkedlifedata.com/resource/pubmed/id/11711901

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2001-11-16
pubmed:abstractText
Myocardial viability can be assessed with rest/24 h redistribution (201)Tl myocardial single photon emission computed tomography (SPECT). The intravenous injection of vasodilators induces an early redistribution of (201)Tl and shortens the total examination time. The aim of this study was to compare the images after injection of linsidomin with the 24 h images. We studied 51 consecutive patients (38 males, 13 females), aged 66+/-11 years, referred for assessment of myocardial viability after acute myocardial infarction. SPECT acquisition at rest (30 projections over 180 degrees, 30 s per projection) was performed 20 min after injection of (201)Tl. A second acquisition (same parameters) was performed 2 min after intravenous injection of linsidomin (2 mg). A delayed acquisition was performed on the following day (50 s per step). Myocardial perfusion at rest was normal in 111 of 255 segments. For the 144 other segments, 24 h images were similar to the images acquired after the injection of linsidomin in 94% of cases (136 of 144 segments). The 24 h images showed partial redistribution that was not present after linsidomin in only eight segments (6%). Injection of linsidomin after rest acquisition can provide a reliable and more rapid assessment of myocardial viability. This very simple protocol (rest/linsidomin (201)Tl myocardial SPECT) can be performed in less than 1 h.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0143-3636
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1313-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Value of linsidomin in assessing myocardial viability with thallium-201 SPECT.
pubmed:affiliation
Service de Médecine Nucléaire, Hôpital Necker-Enfants Malades, AP-HP, 149 rue de Sèvres, 75743 Paris Cedex 15, France. christophe.manoury@nck.ap-hop-paris.fr
pubmed:publicationType
Journal Article