Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 1
pubmed:dateCreated
2001-11-16
pubmed:abstractText
1. The aim of this study was to examine the effect of carbohydrate (CHO) ingestion on changes in ATP and phosphocreatine (PCr) concentrations in different muscle fibre types during prolonged running and relate those changes to the degree of glycogen depletion. 2. Five male subjects performed two runs at 70 % maximum oxygen uptake (.V(O2,max)), 1 week apart. Each subject ingested 8 ml (kg body mass (BM))(-1) of either a placebo (Con trial) or a 5.5 % CHO solution (CHO trial) immediately before each run and 2 ml (kg BM)(-1) every 20 min thereafter. In the Con trial, the subjects ran to exhaustion (97.0 +/- 6.7 min). In the CHO trial, the run was terminated at the time coinciding with exhaustion in the Con trial. Muscle samples were obtained from the vastus lateralis before and after each trial. 3. Carbohydrate ingestion did not affect ATP concentrations. However, it attenuated the decline in PCr concentration by 46 % in type I fibres (CHO: 20 +/- 8 mmol (kg dry matter (DM))(-1); Con: 34 +/- 6 mmol (kg DM)(-1); P < 0.05) and by 36 % in type II fibres (CHO: 30 +/- 5 mmol (kg DM)(-1); Con: 48 +/- 6 mmol (kg DM)(-1); P < 0.05). 4. A 56 % reduction in glycogen utilisation in type I fibres was observed in CHO compared with Con (117 +/- 39 vs. 240 +/- 32 mmol glucosyl units (kg DM)(-1), respectively; P < 0.01), but no difference was observed in type II fibres. 5. It is proposed that CHO ingestion during exhaustive running attenuates the decline in oxidative ATP resynthesis in type I fibres, as indicated by sparing of both PCr and glycogen breakdown. The CHO-induced sparing of PCr, but not glycogen, in type II fibres may reflect differential recruitment and/or role of PCr between fibre types.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-10050023, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-13242493, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-1731757, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-1858860, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-1890634, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-242187, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-2606829, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-2759935, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-3427883, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-3525502, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-4083044, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-4248905, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-4278539, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-4852173, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-5584522, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-6031321, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-6139934, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-7650007, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-7730977, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-7836162, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-8279540, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-8583408, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-8618961, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-8772483, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-8872649, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-8933487, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-9252454, http://linkedlifedata.com/resource/pubmed/commentcorrection/11711582-9458524
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
537
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
305-11
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Phosphocreatine degradation in type I and type II muscle fibres during submaximal exercise in man: effect of carbohydrate ingestion.
pubmed:affiliation
Human Muscle Metabolism Research Group, Loughborough University, Loughborough LE11 3TU, UK. kostas.tzintzas@nottingham.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't