Linked Life Data

11711115

Source:http://linkedlifedata.com/resource/pubmed/id/11711115

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2001-11-16
pubmed:abstractText
Fecal extracts from a pregnant black rhinoceros, Diceros bicornis, were analyzed by radioimmunoassay, HPLC, and by GC-mass spectrometry. From 40 g of dried feces a total of 33 pregnanes in the C(21)O(2) series, including a number of novel 17 alpha epimers were identified. No progesterone was recovered. The principal progesterone metabolite by mass was 5 alpha-pregnan-3 beta,20 alpha-diol (44.5%), which did not cross react with the antibody used in our RIA. The antibody recognized progesterone and pregnanes with 20-one configuration, which when combined made up less than 15% of the total C(21)O(2) steroid mass. Of the 33 pregnanes in the C(21)O(2) series identified, 81%, by mass, were in the 5 alpha-configuration. These results are compared with studies in other rhinoceros species (Asian and Sumatran) in which pregnanes in the 5 beta-configuration are the major fecal metabolites, and the white rhinoceros in which pregnanes in the 5 alpha-configuration are the dominant form.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0039-128X
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
875-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Identification of a series of C(21)O(2) pregnanes from fecal extracts of a pregnant black rhinoceros (Diceros bicornis minor).
pubmed:affiliation
Center for Reproduction of Endangered Species, Zoological Society of San Diego, 1354 Old Globe Way, San Diego, CA 92101, USA. lvalentin@sunstroke.sdsu.edu
pubmed:publicationType
Journal Article