Source:http://linkedlifedata.com/resource/pubmed/id/11704234
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
23
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pubmed:dateCreated |
2001-11-12
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pubmed:abstractText |
The purpose of the study was to determine whether amblyopes show detection loss for second-order spatial information, and if present, whether the loss is explained by the loss of first-order spatial input. We psychophysically determined detection thresholds for the amblyopic and non-amblyopic eyes of five adult amblyopes and the dominant eyes of three control observers. We found that four amblyopic eyes and two non-amblyopic eyes showed second-order loss relative to the control eyes. The second-order loss was greater than the first-order loss at the carrier spatial frequency (first-order input). The extra second-order loss indicates an early amplification of cortical neural loss that we speculate is due to deficient binocular input to second-order neurons.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0042-6989
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2951-60
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11704234-Adult,
pubmed-meshheading:11704234-Amblyopia,
pubmed-meshheading:11704234-Anisometropia,
pubmed-meshheading:11704234-Case-Control Studies,
pubmed-meshheading:11704234-Differential Threshold,
pubmed-meshheading:11704234-Fourier Analysis,
pubmed-meshheading:11704234-Humans,
pubmed-meshheading:11704234-Psychometrics,
pubmed-meshheading:11704234-Psychophysics,
pubmed-meshheading:11704234-Space Perception,
pubmed-meshheading:11704234-Strabismus,
pubmed-meshheading:11704234-Visual Cortex
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pubmed:year |
2001
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pubmed:articleTitle |
Is second-order spatial loss in amblyopia explained by the loss of first-order spatial input?
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pubmed:affiliation |
University of Houston, College of Optometry, The University Eye Institute, 4901 Calhoun Blvd, Houston, TX 77204-6052, USA. ewong@bayou.uh.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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