| pubmed-article:11702779 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C0080347 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C1160520 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:11702779 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:11702779 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11702779 | pubmed:dateCreated | 2001-11-12 | lld:pubmed |
| pubmed-article:11702779 | pubmed:abstractText | Oocytes are released from meiotic prophase I arrest through a process termed oocyte maturation. We present here a genetic characterization of oocyte maturation, using C. elegans as a model system. We show that two TIS11 zinc finger-containing proteins, OMA-1 and OMA-2, express specifically in maturing oocytes and function redundantly in oocyte maturation. Oocytes in oma-1;oma-2 mutants initiate but do not complete maturation and arrest at a defined point in prophase I. Two maturation signal-induced molecular events, including the maintenance of activated MAP kinase, do not occur in Oma oocytes. The Oma prophase arrest is released by inactivation of a MYT-1-like kinase, suggesting that OMA-1 and OMA-2 function upstream of MYT-1 as positive regulators of prophase progression during meiotic maturation. | lld:pubmed |
| pubmed-article:11702779 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11702779 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11702779 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11702779 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11702779 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:11702779 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11702779 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11702779 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:11702779 | pubmed:issn | 1534-5807 | lld:pubmed |
| pubmed-article:11702779 | pubmed:author | pubmed-author:LieKK | lld:pubmed |
| pubmed-article:11702779 | pubmed:author | pubmed-author:RogersEE | lld:pubmed |
| pubmed-article:11702779 | pubmed:author | pubmed-author:LULL | lld:pubmed |
| pubmed-article:11702779 | pubmed:author | pubmed-author:ReubenMM | lld:pubmed |
| pubmed-article:11702779 | pubmed:author | pubmed-author:DetwilerM RMR | lld:pubmed |
| pubmed-article:11702779 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11702779 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:11702779 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11702779 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11702779 | pubmed:pagination | 187-99 | lld:pubmed |
| pubmed-article:11702779 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:11702779 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11702779 | pubmed:articleTitle | Two zinc finger proteins, OMA-1 and OMA-2, are redundantly required for oocyte maturation in C. elegans. | lld:pubmed |
| pubmed-article:11702779 | pubmed:affiliation | Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas 75390-9148, USA. | lld:pubmed |
| pubmed-article:11702779 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11702779 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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