|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2-3
|
|
pubmed:dateCreated |
2001-11-9
|
|
pubmed:abstractText |
It is known that central injection of glucagon-like peptide-1 (GLP-1) suppresses feeding in rats and chicks, but the systems for GLP-1 are still open with special reference to the chick. The present study was done to determine whether a noradrenergic mechanism contributes to the anorexigenic effect of GLP-1 on the neonatal chick. Central administration of norepinephrine (NE) suppressed food intake with narcolepsy as GLP-1 in chicks. However, in spite of that dopamine (DA) did not affect food intake, coadministration of inhibitor of dopamine-beta-hydroxylase (DBH), fusaric acid (FA), attenuated the suppressive effect of GLP-1 on feeding behavior. It is suggested that there may be the interactive relationships between GLP-1 and noradrenergic system in the neonatal chick.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0091-3057
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
70
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
251-5
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:11701195-Animals,
pubmed-meshheading:11701195-Animals, Newborn,
pubmed-meshheading:11701195-Anorexia,
pubmed-meshheading:11701195-Chickens,
pubmed-meshheading:11701195-Dopamine Agents,
pubmed-meshheading:11701195-Dose-Response Relationship, Drug,
pubmed-meshheading:11701195-Eating,
pubmed-meshheading:11701195-Fusaric Acid,
pubmed-meshheading:11701195-Glucagon,
pubmed-meshheading:11701195-Glucagon-Like Peptide 1,
pubmed-meshheading:11701195-Injections, Intraventricular,
pubmed-meshheading:11701195-Male,
pubmed-meshheading:11701195-Norepinephrine,
pubmed-meshheading:11701195-Peptide Fragments,
pubmed-meshheading:11701195-Protein Precursors
|
|
pubmed:articleTitle |
Intracerebroventricular injection of fusaric acid attenuates the anorexia by glucagon-like peptide-1 in the neonatal chick.
|
|
pubmed:affiliation |
Laboratory of Animal Science, Department of Agrobiological Science, Faculty of Agriculture, Ehime University, Matsuyama 790-8566, Japan. bungo@agr.ehime-u.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
