Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2001-11-7
pubmed:abstractText
The purpose of this study was to determine the relationship between changes in maximal oxygen uptake (VO2 max) and submaximal markers of aerobic fitness and changes in risk factors for cardiovascular disease (CVD) and non-insulin-dependent diabetes mellitus (NIDDM) consequent to a 20-week endurance training program. The 502 participants in this study were healthy and previously sedentary men (n = 250) and women (n = 252) of varying age (17 to 65 years) and race (blacks n = 142; whites n = 360) who had completed the HERITAGE Family Study testing and training protocol. Following baseline measurements, participants trained on cycle ergometers 3 days/week for a total of 60 exercise sessions starting at the heart rate (HR) associated with 55% of VO2 max for 30 minutes/session. This was progressively increased to the HR associated with 75% of VO2 max for 50 minutes/session, which was maintained during the last 6 weeks. VO2 max, heart rate at 50 W, power output at 60% of VO2 max, lipids and lipoproteins, resting blood pressure, body composition including abdominal fat (computed tomography [CT] scan), and blood glucose and insulin at rest and at peak following an intravenous glucose tolerance test (IVGTT) were determined both before and after training. Following training, there were significant increases in VO2 max (16%) and the power output at 60% of VO2 max and a significant decrease in HR at 50 W. These changes in markers of aerobic fitness were significantly correlated only to the changes in the body composition variables and the lipids and lipoproteins. Further, there was considerable individual variation in response for all variables studied. Finally, when risk factor data were analyzed by quartile of change in VO2 max, there were few significant relationships. It is concluded that there is a significant relationship between changes in markers of aerobic fitness and changes in several risk factors for CVD and NIDDM. However, the magnitude of these relationships is small.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0026-0495
pubmed:author
pubmed:copyrightInfo
Copyright 2001 by W.B. Saunders Company
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1255-63
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:11699041-Adolescent, pubmed-meshheading:11699041-Adult, pubmed-meshheading:11699041-African Continental Ancestry Group, pubmed-meshheading:11699041-Aged, pubmed-meshheading:11699041-Blood Glucose, pubmed-meshheading:11699041-Blood Pressure, pubmed-meshheading:11699041-Body Composition, pubmed-meshheading:11699041-Canada, pubmed-meshheading:11699041-Cardiovascular Diseases, pubmed-meshheading:11699041-Diabetes Mellitus, Type 2, pubmed-meshheading:11699041-European Continental Ancestry Group, pubmed-meshheading:11699041-Exercise, pubmed-meshheading:11699041-Exercise Test, pubmed-meshheading:11699041-Family, pubmed-meshheading:11699041-Female, pubmed-meshheading:11699041-Glucose Tolerance Test, pubmed-meshheading:11699041-Heart Rate, pubmed-meshheading:11699041-Humans, pubmed-meshheading:11699041-Insulin, pubmed-meshheading:11699041-Lipids, pubmed-meshheading:11699041-Lipoproteins, pubmed-meshheading:11699041-Male, pubmed-meshheading:11699041-Middle Aged, pubmed-meshheading:11699041-Oxygen Consumption, pubmed-meshheading:11699041-Physical Endurance, pubmed-meshheading:11699041-Physical Exertion, pubmed-meshheading:11699041-Risk Factors, pubmed-meshheading:11699041-United States
pubmed:year
2001
pubmed:articleTitle
Relationship of changes in maximal and submaximal aerobic fitness to changes in cardiovascular disease and non-insulin-dependent diabetes mellitus risk factors with endurance training: the HERITAGE Family Study.
pubmed:affiliation
Department of Health and Kinesiology, Texas A&M University, College Station, TX 77843-4243, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Multicenter Study