Source:http://linkedlifedata.com/resource/pubmed/id/11693422
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2001-11-5
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pubmed:abstractText |
This study was designed to evaluate osteointegration of HA-coated and uncoated titanium and stainless steel screws in the cortical bone of long-term (24 months) ovariectomized sheep (OVX group), in comparison with Sham-aged sheep (control group). The screws were tested biomechanically (extraction torque) and histomorphometrically (affinity index: Al) 12 weeks after their implantation in tibial diaphyses. Tibial cortical bone parameters showed significant differences between the groups, showing a reduction of the selected parameters in the OVX group. ANOVA showed significant effects for both material and ovariectomy factors on obtained extraction torque (material: F=159.26, p < 0.0005; ovariectomy: F=20.04, p < 0.0005) and Al data (material: F=8.04, p < 0.001; ovariectomy: F=7, 17, p < 0.05). In both groups the extraction torque for coated screws of both materials was significantly higher than for uncoated screws, and uncoated titanium had a better extraction torque than uncoated stainless steel. In the OVX group, the HA-coated stainless steel and titanium Al data were significantly higher than uncoated Al data. In conclusion, the biomechanical and histomorphological results obtained suggest employing HA-coated screws in the presence of osteopenic cortical bone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0391-3988
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
649-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11693422-Animals,
pubmed-meshheading:11693422-Biomechanics,
pubmed-meshheading:11693422-Bone Diseases, Metabolic,
pubmed-meshheading:11693422-Bone Screws,
pubmed-meshheading:11693422-Coated Materials, Biocompatible,
pubmed-meshheading:11693422-Female,
pubmed-meshheading:11693422-Ovariectomy,
pubmed-meshheading:11693422-Prostheses and Implants,
pubmed-meshheading:11693422-Random Allocation,
pubmed-meshheading:11693422-Sheep,
pubmed-meshheading:11693422-Stainless Steel,
pubmed-meshheading:11693422-Tibia,
pubmed-meshheading:11693422-Titanium
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pubmed:year |
2001
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pubmed:articleTitle |
Tibial implants: biomechanical and histomorphometric studies of hydroxyapatite-coated and uncoated stainless steel and titanium screws in long-term ovariectomized sheep.
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pubmed:affiliation |
Experimental Surgery Department, Codivilla-Putti Research Institute, Rizzoli Orthopaedic Institute, Bologna, Italy. michele.rocca@ior.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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