Linked Life Data

11692472

Source:http://linkedlifedata.com/resource/pubmed/id/11692472

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-11-5
pubmed:abstractText
These data demonstrate that regression of biopsy-proven glomerulosclerosis can be achieved in various experimental settings. The potential importance of the RAS in renal fibrosis is underscored by the effectiveness of therapies that aim to inhibit its manifold actions, including induction of PAI-1. An understanding of the interactions of the RAS with the immune response, aldosterone, and PAI-1, as well as the dynamic control of cell proliferation, apoptosis, and regeneration, is now evolving. Ongoing studies will establish which of these recent provocative findings from animal models are relevant to human diseases, and may lead to optimal therapies to fore-stall progression and perhaps even induce regression of sclerosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0084-5957
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-87
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Renal fibrosis and the renin-angiotensin system.
pubmed:affiliation
Vanderbilt University School of Medicine, Renal/EM Laboratory, Vanderbilt University Medical Center, Nashville, Tenn., USA.
pubmed:publicationType
Journal Article, Review