rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-11-5
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pubmed:abstractText |
Allergic rhinitis and asthma show many similarities in their epithelial and inflammatory responses to allergens. However, one notable difference is that disruption and desquamation of the epithelium is a characteristic feature of asthma, whereas in perennial allergic rhinitis the epithelium is intact and thickened. One reason for this might be differing expression of matrix metalloproteinases (MMPs) or their inhibitors (TIMPs). There are few published data on the presence of MMPs or TIMPs in the nasal mucosa in rhinitis.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0091-6749
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
108
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
791-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11692106-Blotting, Western,
pubmed-meshheading:11692106-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:11692106-Humans,
pubmed-meshheading:11692106-Matrix Metalloproteinase 1,
pubmed-meshheading:11692106-Matrix Metalloproteinase 2,
pubmed-meshheading:11692106-Matrix Metalloproteinase 3,
pubmed-meshheading:11692106-Matrix Metalloproteinase 9,
pubmed-meshheading:11692106-Matrix Metalloproteinases,
pubmed-meshheading:11692106-Nasal Mucosa,
pubmed-meshheading:11692106-RNA, Messenger,
pubmed-meshheading:11692106-Rhinitis, Allergic, Perennial,
pubmed-meshheading:11692106-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:11692106-Tissue Inhibitor of Metalloproteinase-2
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pubmed:year |
2001
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pubmed:articleTitle |
Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis.
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pubmed:affiliation |
Department of Otolaryngology, St Bartholomew's and the Royal London School of Medicine and Dentistry, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|