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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-11-5
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pubmed:abstractText |
Immunostimulatory DNA sequences (ISS) inhibit eosinophilic inflammation and airway hyperreactivity in mouse models of asthma. In vitro ISS activate natural killer (NK) cells to secrete IFN-gamma, and this cytokine is hypothesized to contribute to the antiallergic effect of ISS in vivo.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0091-6749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
759-63
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11692101-Adjuvants, Immunologic,
pubmed-meshheading:11692101-Animals,
pubmed-meshheading:11692101-Asthma,
pubmed-meshheading:11692101-Bone Marrow Diseases,
pubmed-meshheading:11692101-Bronchial Hyperreactivity,
pubmed-meshheading:11692101-Bronchoconstrictor Agents,
pubmed-meshheading:11692101-Cells, Cultured,
pubmed-meshheading:11692101-DNA,
pubmed-meshheading:11692101-Eosinophilia,
pubmed-meshheading:11692101-Female,
pubmed-meshheading:11692101-Interferon-gamma,
pubmed-meshheading:11692101-Killer Cells, Natural,
pubmed-meshheading:11692101-Lymphocyte Depletion,
pubmed-meshheading:11692101-Methacholine Chloride,
pubmed-meshheading:11692101-Mice,
pubmed-meshheading:11692101-Mice, Inbred C57BL,
pubmed-meshheading:11692101-Ovalbumin,
pubmed-meshheading:11692101-Pulmonary Eosinophilia
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pubmed:year |
2001
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pubmed:articleTitle |
Immunostimulatory DNA mediates inhibition of eosinophilic inflammation and airway hyperreactivity independent of natural killer cells in vivo.
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pubmed:affiliation |
Department of Medicine, University of California, San Diego, La Jolla 92093-0635, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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