Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
2001-11-5
pubmed:abstractText
During studies examining the rate of human immunodeficiency virus type 1 (HIV-1) mutation in a single cycle of replication, the 5' long terminal repeat of one progeny provirus was found to contain an insertion of 147 bp including an entire tRNA sequence as well as an additional 66 bp insertion of nonviral origin. Database searches revealed that 65 of 66 bp aligned with the human CpG island sequence found on chromosomes 6, 14, and 17. Therefore it seems probable that it is of human cellular sequence origin and was transduced by HIV-1. This is the first demonstration that HIV-1 can capture a cellular sequence. The site of integration of the parental provirus was mapped to chromosome 1p32.1. Sequence with homology to the transduced CpG island was not found on chromosome 1, suggesting that the transduced cellular sequence was not linked to the site of viral integration.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-10516026, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-10627533, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-11072081, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-11120884, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-1371365, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-1505946, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-1600751, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-1645786, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-1700824, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2153250, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2170682, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2201018, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2214018, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2418216, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2825348, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2897475, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-2988784, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-3040055, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7474162, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7494312, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7507249, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7529228, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7549424, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7685401, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7688465, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-7692080, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-8445707, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-8676479, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-8824790, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-9126266, http://linkedlifedata.com/resource/pubmed/commentcorrection/11689674-9756895
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11902-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Transduction of cellular sequence by a human immunodeficiency virus type 1-derived vector.
pubmed:affiliation
Department of Molecular Genetics & Microbiology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.