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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2001-11-5
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pubmed:abstractText |
The average 50% inhibitory concentration (IC(50)) values for AD169 were 0.22 +/- 0.09 microM 1263W94 and 5.36 +/- 0.12 microM ganciclovir. For 35 human cytomegalovirus (HCMV) clinical isolates the average IC(50) was 0.42 +/- 0.09 microM 1263W94, and for 26 ganciclovir-susceptible HCMV clinical isolates the average IC(50) was 3.78 +/- 1.62 microM ganciclovir. Nine HCMV clinical isolates that were resistant to ganciclovir were completely susceptible to 1263W94.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-10194460,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-10438815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-10480260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-10549385,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-10680738,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-11181123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-11557492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-1656826,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-1666492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-7785989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-7797920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-7876604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-8781616,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-8786764,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-8993860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9129070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9420278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9498461,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9542916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9573236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9736542,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11687477-9736557
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1071-412X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1279-81
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11687477-Anti-HIV Agents,
pubmed-meshheading:11687477-Antiviral Agents,
pubmed-meshheading:11687477-Benzimidazoles,
pubmed-meshheading:11687477-Cytomegalovirus,
pubmed-meshheading:11687477-DNA, Viral,
pubmed-meshheading:11687477-Fibroblasts,
pubmed-meshheading:11687477-Flow Cytometry,
pubmed-meshheading:11687477-Ganciclovir,
pubmed-meshheading:11687477-Humans,
pubmed-meshheading:11687477-Inhibitory Concentration 50,
pubmed-meshheading:11687477-Nucleic Acid Hybridization,
pubmed-meshheading:11687477-Ribonucleosides,
pubmed-meshheading:11687477-Viral Plaque Assay
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pubmed:year |
2001
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pubmed:articleTitle |
Inhibition of ganciclovir-susceptible and -resistant human cytomegalovirus clinical isolates by the benzimidazole L-riboside 1263W94.
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pubmed:affiliation |
Center for Immunology and Microbial Disease, Albany Medical College, Albany, New York 12208, USA. mcsharj@mail.amc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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