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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1975-7-31
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pubmed:abstractText |
Mice were immunized to the intestinal stage of T. spiralis by using infections terminated with methyridine before production of newborn larvae had commenced. The muscle larvae which encysted following a normal complete challenge infection were reduced by 87 and 95% in immunized mice. No statistically significant reduction in a challenge infection of intravenously injected parenteral larvae was produced (8% and 15% actual reduction). Previous work has shown that adult worms in a challenge infection are stunted and expelled earlier as well as having a reduced fecundity; it is concluded that the immunity generated by the intestinal stage is largely specific in its action to that phase in a challenge infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
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pubmed:issn |
0022-149X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1168664-Animals,
pubmed-meshheading:1168664-Antibody Formation,
pubmed-meshheading:1168664-Female,
pubmed-meshheading:1168664-Immunization,
pubmed-meshheading:1168664-Injections, Intravenous,
pubmed-meshheading:1168664-Intestines,
pubmed-meshheading:1168664-Larva,
pubmed-meshheading:1168664-Mice,
pubmed-meshheading:1168664-Muscles,
pubmed-meshheading:1168664-Pyridines,
pubmed-meshheading:1168664-Trichinella,
pubmed-meshheading:1168664-Trichinellosis
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pubmed:year |
1975
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pubmed:articleTitle |
Immunity to Trichinella spiralis VI. The specificity of the immune response stimulated by the intestinal stage.
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pubmed:publicationType |
Journal Article
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