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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
18
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pubmed:dateCreated |
2001-10-30
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pubmed:abstractText |
Pulmonary arterial hypertension is characterized by increased pulmonary vascular resistance secondary to a decrease in the caliber and number of pulmonary vascular channels. We hypothesized that the targeted overexpression of an angiogenic factor within the lung would potentially minimize the development and progression of pulmonary arterial hypertension by preventing the loss of existing vessels or by inducing the development of new blood vessels within the lung.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
30
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2242-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11684638-Animals,
pubmed-meshheading:11684638-Cell Transplantation,
pubmed-meshheading:11684638-Cells, Cultured,
pubmed-meshheading:11684638-Disease Models, Animal,
pubmed-meshheading:11684638-Endothelial Growth Factors,
pubmed-meshheading:11684638-Fluorescent Dyes,
pubmed-meshheading:11684638-Gene Therapy,
pubmed-meshheading:11684638-Gene Transfer Techniques,
pubmed-meshheading:11684638-Hypertension, Pulmonary,
pubmed-meshheading:11684638-Lung,
pubmed-meshheading:11684638-Lymphokines,
pubmed-meshheading:11684638-Microcirculation,
pubmed-meshheading:11684638-Monocrotaline,
pubmed-meshheading:11684638-Muscle, Smooth, Vascular,
pubmed-meshheading:11684638-Pulmonary Circulation,
pubmed-meshheading:11684638-Rats,
pubmed-meshheading:11684638-Rats, Inbred F344,
pubmed-meshheading:11684638-Transplantation, Isogeneic,
pubmed-meshheading:11684638-Treatment Outcome,
pubmed-meshheading:11684638-Vascular Endothelial Growth Factor A,
pubmed-meshheading:11684638-Vascular Endothelial Growth Factors
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pubmed:year |
2001
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pubmed:articleTitle |
Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.
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pubmed:affiliation |
Division of Cardiac Surgery, University of Toronto, Terrence Donnelly Heart Centre, St Michael's Hospital, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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