Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
2001-10-30
pubmed:abstractText
Proinflammatory cytokines like tumor necrosis factor-alpha and oxidative stress induce apoptotic cell death in endothelial cells (ECs). Systemic inflammation and increased oxidative stress in congestive heart failure (CHF) coincide with enhanced EC apoptosis and the development of endothelial dysfunction. Therefore, we investigated the effects of antioxidative vitamin C therapy on EC apoptosis in CHF patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1524-4539
pubmed:author
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2182-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:11684628-Administration, Oral, pubmed-meshheading:11684628-Adult, pubmed-meshheading:11684628-Aged, pubmed-meshheading:11684628-Angiotensin II, pubmed-meshheading:11684628-Apoptosis, pubmed-meshheading:11684628-Ascorbic Acid, pubmed-meshheading:11684628-Biological Markers, pubmed-meshheading:11684628-Cell Survival, pubmed-meshheading:11684628-Cells, Cultured, pubmed-meshheading:11684628-Dose-Response Relationship, Drug, pubmed-meshheading:11684628-Drug Administration Schedule, pubmed-meshheading:11684628-Endothelium, Vascular, pubmed-meshheading:11684628-Enzyme Inhibitors, pubmed-meshheading:11684628-Female, pubmed-meshheading:11684628-Heart Failure, pubmed-meshheading:11684628-Humans, pubmed-meshheading:11684628-Injections, Intravenous, pubmed-meshheading:11684628-Male, pubmed-meshheading:11684628-Middle Aged, pubmed-meshheading:11684628-Oxidative Stress, pubmed-meshheading:11684628-Prospective Studies, pubmed-meshheading:11684628-Thiobarbituric Acid Reactive Substances, pubmed-meshheading:11684628-Tumor Necrosis Factor-alpha
pubmed:year
2001
pubmed:articleTitle
Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.
pubmed:affiliation
Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't