rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
18
|
pubmed:dateCreated |
2001-10-30
|
pubmed:abstractText |
Proinflammatory cytokines like tumor necrosis factor-alpha and oxidative stress induce apoptotic cell death in endothelial cells (ECs). Systemic inflammation and increased oxidative stress in congestive heart failure (CHF) coincide with enhanced EC apoptosis and the development of endothelial dysfunction. Therefore, we investigated the effects of antioxidative vitamin C therapy on EC apoptosis in CHF patients.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1524-4539
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
30
|
pubmed:volume |
104
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2182-7
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11684628-Administration, Oral,
pubmed-meshheading:11684628-Adult,
pubmed-meshheading:11684628-Aged,
pubmed-meshheading:11684628-Angiotensin II,
pubmed-meshheading:11684628-Apoptosis,
pubmed-meshheading:11684628-Ascorbic Acid,
pubmed-meshheading:11684628-Biological Markers,
pubmed-meshheading:11684628-Cell Survival,
pubmed-meshheading:11684628-Cells, Cultured,
pubmed-meshheading:11684628-Dose-Response Relationship, Drug,
pubmed-meshheading:11684628-Drug Administration Schedule,
pubmed-meshheading:11684628-Endothelium, Vascular,
pubmed-meshheading:11684628-Enzyme Inhibitors,
pubmed-meshheading:11684628-Female,
pubmed-meshheading:11684628-Heart Failure,
pubmed-meshheading:11684628-Humans,
pubmed-meshheading:11684628-Injections, Intravenous,
pubmed-meshheading:11684628-Male,
pubmed-meshheading:11684628-Middle Aged,
pubmed-meshheading:11684628-Oxidative Stress,
pubmed-meshheading:11684628-Prospective Studies,
pubmed-meshheading:11684628-Thiobarbituric Acid Reactive Substances,
pubmed-meshheading:11684628-Tumor Necrosis Factor-alpha
|
pubmed:year |
2001
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pubmed:articleTitle |
Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.
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pubmed:affiliation |
Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|