Source:http://linkedlifedata.com/resource/pubmed/id/11682226
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2001-10-29
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pubmed:abstractText |
Studies on the capabilities of flow injection analysis (FIA) combined with on-line characterisation of model compounds via a combination of diode array UV, 1H-NMR, FT-IR spectroscopy and mass spectrometry are described. Using this combination of spectrometers enabled the on-flow collection of UV, 1H-NMR, IR and MS for a range of model compounds. Samples were introduced into the system as solutions in deuterium oxide in concentrations ranging from 1.4 to 8.4 mg ml(-1). A sample volume of 100 microl was used for FIA at a flow rate of 1 ml min(-1). From these studies a practical working quantity of ca. 140 microg/sample of analyte was determined which provided characteristic spectra.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0731-7085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-200
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11682226-4-Aminobenzoic Acid,
pubmed-meshheading:11682226-Flow Injection Analysis,
pubmed-meshheading:11682226-Magnetic Resonance Spectroscopy,
pubmed-meshheading:11682226-Mass Spectrometry,
pubmed-meshheading:11682226-Spectrophotometry, Infrared,
pubmed-meshheading:11682226-Spectrophotometry, Ultraviolet,
pubmed-meshheading:11682226-Spectroscopy, Fourier Transform Infrared,
pubmed-meshheading:11682226-Spectrum Analysis
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pubmed:year |
2002
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pubmed:articleTitle |
Flow injection analysis with multiple on-line spectroscopic analysis (UV, IR, 1H-NMR and MS).
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pubmed:affiliation |
AstraZeneca Pharmaceuticals, Drug Metabolism & Pharmacokinetics Department, Mereside, Alderley Park, Macclesfield, SK10 4TG, Cheshire, UK.
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pubmed:publicationType |
Journal Article
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