Linked Life Data

11680742

Source:http://linkedlifedata.com/resource/pubmed/id/11680742

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
2001-10-26
pubmed:abstractText
Both pentachlorophenol (PCP) and copper compounds have been widely used as wood preservatives, and are commonly found not only in the area near wood-preserving facilities, but also in body fluids and tissues of people who are not occupationally exposed to them. In this study, we found that exposing bacteria to a combination of PCP and copper at non- or sub-toxic concentrations resulted in enhanced cytotoxic effect in a synergistic mode as indicated by both the inhibition of growth and the lowering of the colony-forming ability. The toxicity of the combination PCP/Cu(II) was relieved by hydrophilic chelating agents, thiol compounds and adventitious proteins, but was markedly potentiated by low levels of the lipophilic metal chelating agents.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0045-6535
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
463-70
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Synergistic cytotoxicity between pentachlorophenol and copper in a bacterial model.
pubmed:affiliation
Department of Cellular Biochemistry, Hebrew University-Hadassah School of Medicine, Jerusalem, Israel. benzhan.zhu@orst.edu
pubmed:publicationType
Journal Article