|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005775,
umls-concept:C0017262,
umls-concept:C0018787,
umls-concept:C0185117,
umls-concept:C0237477,
umls-concept:C0387583,
umls-concept:C0741847,
umls-concept:C1135183,
umls-concept:C1330125,
umls-concept:C1948023,
umls-concept:C2911684
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2001-10-24
|
|
pubmed:abstractText |
Cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes catalyze the initial step in the formation of prostaglandins, which have a role in the regulation of circulation and in inflammatory reactions. As hypoxia is reported to stimulate the expression of COX-2, we have investigated the effects of bypass circulation and cardioplegic arrest on the expression COX-1 and COX-2 in the myocardium of porcine hearts.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1010-7940
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
20
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
992-5
|
|
pubmed:dateRevised |
2005-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:11675186-Animals,
pubmed-meshheading:11675186-Blotting, Northern,
pubmed-meshheading:11675186-Blotting, Western,
pubmed-meshheading:11675186-Cardiopulmonary Bypass,
pubmed-meshheading:11675186-Cyclooxygenase 1,
pubmed-meshheading:11675186-Cyclooxygenase 2,
pubmed-meshheading:11675186-Heart Arrest, Induced,
pubmed-meshheading:11675186-Isoenzymes,
pubmed-meshheading:11675186-Myocardium,
pubmed-meshheading:11675186-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:11675186-Proteins,
pubmed-meshheading:11675186-RNA, Messenger,
pubmed-meshheading:11675186-Swine
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Stimulated expression of cyclooxygenase-2 in porcine heart after bypass circulation and cardioplegic arrest.
|
|
pubmed:affiliation |
Department of Physiology, University of Turku, Kiinamyllynkatu 10, 20520, Turku, Finland.
|
|
pubmed:publicationType |
Journal Article
|
