Linked Life Data

11673331

Source:http://linkedlifedata.com/resource/pubmed/id/11673331

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 11
pubmed:dateCreated
2001-10-23
pubmed:abstractText
Much research on visual function in migraine has examined early aspects of visual processing, often using detection or discrimination measures and stimuli reported to trigger an attack, e.g. striped patterns or flickering lights. Differences between people with and without migraine have been attributed to abnormal cortical processing in migraine, variously described by interictal hyperexcitability, heightened responsiveness, a lack of habituation and/or a lack of intra-cortical inhibition. Here, two experiments are presented that explore a uniquely cortical phenomenon, pattern or contrast adaptation, one using the motion after-effect, one the tilt after-effect. Pattern adaptation reflects specific interactions between groups of neurones and is therefore ideally suited to address proposed models of cortical function in migraine. These models lead to specific predictions in an adaptation study: there should be smaller effects in people with migraine than in people without. The results from both adaptation experiments, however, revealed larger effects in migraine sufferers than in headache-free control subjects. There were no differences between migraine subgroups classified according to the presence or absence of aura. These results are discussed in terms of models of cortical function in migraine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0006-8950
pubmed:author
pubmed:issnType
Print
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2310-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Increased visual after-effects following pattern adaptation in migraine: a lack of intracortical excitation?
pubmed:affiliation
School of Psychology, Birkbeck College, London, UK. a.shepaerd@psychology.bbk.ac.uk
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't