Linked Life Data

11673055

Source:http://linkedlifedata.com/resource/pubmed/id/11673055

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-10-23
pubmed:abstractText
While cardiac myocytes are not generally considered conventional cellular targets of retroviral infection with HIV-1, the increasing recognition of AIDS related cardiomyopathy has raised important questions as to the viral pathogenesis. Our laboratory has explored the role of simian immunodeficiency viral (SIV) infection in non-human primates as a suitable large-animal model to examine cardiac involvement. Our data suggest that in the presence of inflammatory myocarditis, SIV is localized to CD4 bearing inflammatory cells and not cardiac myocytes, suggesting that the heart may be an innocent bystander in AIDS cardiomyopathy.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1050-1738
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
242-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
SIV cardiomyopathy in non-human primates.
pubmed:affiliation
Department of Medicine, Allegheny General Hospital, MCP-Hahnemann University School of Medicine, Pittsburgh, PA 15212, USA. rshannon@wpahs.org
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review