Linked Life Data

11668649

Source:http://linkedlifedata.com/resource/pubmed/id/11668649

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-10-22
pubmed:abstractText
A sexually dimorphic nucleus is located in the preoptic area of Japanese quail and plays a key role in the activation of male copulatory behavior. The medial preoptic nucleus (POM) is significantly larger in adult male than in adult female quail. Its volume is steroid-sensitive in adulthood and consequently decreases after castration but is restored to normal levels by a treatment with exogenous testosterone. This volumetric difference appears to result only from a sex difference in the adult hormonal milieu and is not affected by embryonic treatments that permanently modify sexual behavior (no organizational effects). In contrast, some cytoarchitectonic features of the POM such as the size of neurons in the dorso-lateral part of nucleus appear to be irreversibly affected by embryonic steroids. The POM is characterized by the presence of a wide variety of neurotransmitters, neuropeptides, and receptors and can be specifically identified by the presence of a dense cluster of aromatase-immunoreactive cells, by a high density of neurotensin-immunoreactive cells and fibers and by a dense vasotocinergic innervation. Some of these neurochemical markers of the dimorphic nucleus are themselves modulated by steroids. Many of these neurochemical changes appear to play a causal role in the control of male sexual behavior. The quail POM thus represents an excellent model for the analysis of steroid-induced brain plasticity in a behaviorally relevant context.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1059-910X
pubmed:author
pubmed:copyrightInfo
Copyright 2001 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
364-74
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Sexual dimorphism in the neuronal circuits of the quail preoptic and limbic regions.
pubmed:affiliation
Rita Levi Montalcini Center for Brain Repair, Department of Anatomy, Pharmacology and Forensic Medicine, Laboratory of Neuroendocrinology, University of Torino, Torino, I-10126 Italy. giancarlo.panzica@unito.it
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't