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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-10-22
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pubmed:abstractText |
The diagnosis of melanoma can be difficult because of shared cytomorphology with other malignant neoplasms. The most commonly used melanocytic markers, anti-S-100 protein and HMB-45 antigen, have limited specificity and sensitivity, respectively. Microphthalmia transcription factor (Mitf) is a nuclear transcription factor critical for the development and survival of melanocytes and has been shown as a sensitive and specific marker for melanoma in histologic specimens.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/MITF protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Melanoma-Specific Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Microphthalmia-Associated...,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/S100 Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
337-43
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11668469-Antibodies, Monoclonal,
pubmed-meshheading:11668469-Antigens, Neoplasm,
pubmed-meshheading:11668469-DNA-Binding Proteins,
pubmed-meshheading:11668469-Humans,
pubmed-meshheading:11668469-Immunohistochemistry,
pubmed-meshheading:11668469-Melanoma,
pubmed-meshheading:11668469-Melanoma-Specific Antigens,
pubmed-meshheading:11668469-Microphthalmia-Associated Transcription Factor,
pubmed-meshheading:11668469-Neoplasm Proteins,
pubmed-meshheading:11668469-Predictive Value of Tests,
pubmed-meshheading:11668469-Retrospective Studies,
pubmed-meshheading:11668469-S100 Proteins,
pubmed-meshheading:11668469-Sensitivity and Specificity,
pubmed-meshheading:11668469-Skin Neoplasms,
pubmed-meshheading:11668469-Transcription Factors,
pubmed-meshheading:11668469-Tumor Markers, Biological
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pubmed:year |
2001
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pubmed:articleTitle |
Microphthalmia transcription factor: a sensitive and specific marker for malignant melanoma in cytologic specimens.
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pubmed:affiliation |
Department of Pathology, University of Alabama at Birmingham, 35249-6823, USA. cdorvault@earthlink.net
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pubmed:publicationType |
Journal Article,
Comparative Study
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