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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1975-12-11
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pubmed:abstractText |
As evidenced from the action of acetone extracts of the mucous layer of the human appendix, these extracts contain a substance capable of bleaching the frog's skin. Model experiments with 0.1% adrenaline, 0.2% noradrenaline, 2.5% hydrocortisone and solutions of various concentrations of synthesized melatonin permitted to identify the above substance as melatonin. The bleaching aciton dependence on the number of enterochromaffin cells (Ec-cells) in the mucous layer of the appendix, and the presence of serotonin in Ec-cells reveal a connection between melatonin and Ec-cells. An average content of 5-methoxy-N-acetyltryptamine in the human appendix amounts to 0.004 mg per 100 Ec-cells. It is suggested that the epiphysis and enterochromaffin cells compose a common functional neuroendocrine system playing a definite role in maintaining the homeostasis of the organism.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0041-3771
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1047-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1166520-Animals,
pubmed-meshheading:1166520-Anura,
pubmed-meshheading:1166520-Appendix,
pubmed-meshheading:1166520-Chromaffin System,
pubmed-meshheading:1166520-Enterochromaffin Cells,
pubmed-meshheading:1166520-Humans,
pubmed-meshheading:1166520-Intestinal Mucosa,
pubmed-meshheading:1166520-Melanophores,
pubmed-meshheading:1166520-Melatonin,
pubmed-meshheading:1166520-Skin,
pubmed-meshheading:1166520-Time Factors,
pubmed-meshheading:1166520-Tissue Extracts
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pubmed:year |
1975
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pubmed:articleTitle |
[5-Methoxy-N-acetyltryptamine (melatonin) in enterochromaffin cells].
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pubmed:publicationType |
Journal Article,
English Abstract
|