Linked Life Data

1164671

Source:http://linkedlifedata.com/resource/pubmed/id/1164671

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1975-12-11
pubmed:abstractText
The uptake of dopamine (DA) by synaptosomes from the hypothalamus and striatum was reduced in healthy ageing mice at DA concentrations below 10(-7) M. Kinectic analysis indicates that ageing increases the Km of high affinity DA uptake processes by about 35%, but does not alter alter Vmax. l-Tyrosine and serotonin uptake at low concentrations was unaltered by ageing in the striatum and hypothalamus; no changes of L-norepinephrine uptake were found in the hypothalamus. We conclude that ageing may selectively affect DA uptake processes by neuronal membranes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-215
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Ageing and dopamine uptake by subcellular fractions of the C57BL/6J male mouse brain.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.