Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2001-10-19
pubmed:abstractText
This clinical and economical study compared two glycopeptides regimen i.e., vancomycin and teicoplanin in the treatment of osteoarticular infection involving methicillin-resistant staphylococcus. After randomization, 15 patients (group 1) received vancomycin (23 F per gram) in continuous infusion through a central venous catheter and 15 others (group 2) intramuscular teicoplanin (311-357 F a 400 mg vial). The clinical study focused on treatment tolerance in an in-patient setting as well as in a non in-patient one. The cost analysis focused on total expenses including those of antibiotics, those of medical devices for antibiotic administration and those of the complications caused by the antibiotics use. Total expenses per patient averaged 8744 F with vancomycin and 8555 F with teicoplanin (NS). The apparent money saving by using a cheap antibiotic (i.e. vancomycin) was illusionary as one took in account the expenses for medical devices e.g., central venous catheters required to administer vancomycin and the complications due to the use of these devices.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0369-8114
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
587-96
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11642024-Acute Disease, pubmed-meshheading:11642024-Aged, pubmed-meshheading:11642024-Anti-Bacterial Agents, pubmed-meshheading:11642024-Arthritis, Infectious, pubmed-meshheading:11642024-Catheterization, Central Venous, pubmed-meshheading:11642024-Chronic Disease, pubmed-meshheading:11642024-Drug Costs, pubmed-meshheading:11642024-Drug Hypersensitivity, pubmed-meshheading:11642024-Female, pubmed-meshheading:11642024-France, pubmed-meshheading:11642024-Health Care Costs, pubmed-meshheading:11642024-Humans, pubmed-meshheading:11642024-Infusions, Intravenous, pubmed-meshheading:11642024-Kidney Diseases, pubmed-meshheading:11642024-Male, pubmed-meshheading:11642024-Methicillin Resistance, pubmed-meshheading:11642024-Middle Aged, pubmed-meshheading:11642024-Osteitis, pubmed-meshheading:11642024-Phlebitis, pubmed-meshheading:11642024-Pneumothorax, pubmed-meshheading:11642024-Postoperative Complications, pubmed-meshheading:11642024-Prospective Studies, pubmed-meshheading:11642024-Prosthesis-Related Infections, pubmed-meshheading:11642024-Staphylococcal Infections, pubmed-meshheading:11642024-Staphylococcus, pubmed-meshheading:11642024-Staphylococcus aureus, pubmed-meshheading:11642024-Staphylococcus epidermidis, pubmed-meshheading:11642024-Syndrome, pubmed-meshheading:11642024-Teicoplanin, pubmed-meshheading:11642024-Vancomycin
pubmed:year
2001
pubmed:articleTitle
[The comparative costs of vancomycin treatment versus teicoplanin in osteoarticular infection caused by methicillin-resistant staphylococci].
pubmed:affiliation
Clinique chirurgicale orthopédique, Hôtel-Dieu, CHR 44093 Nantes, France. charles.phamdang@chu-nantes.fr
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Randomized Controlled Trial