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pubmed:abstractText |
Defensins, a major family of antimicrobial peptides, are small cationic, cysteine-rich peptides with a wide range of antimicrobial activity. In human, beta-defensin-1 was isolated from urine and cervical mucous suggesting that this peptide plays an antimicrobial role in the genitourinary tract. Beta-defensin-2 was identified in psoriatic scale produced by keratinocytes suggesting that this peptide contributes to defend the expansive surface of the integuments.
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pubmed:affiliation |
Department of Dermatology, College of Medicine, Chung Ang University Hospital, 82-1, 2-ka, Pildong, Chung-ku, 100-272, Seoul, South Korea.
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