Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1975-12-4
pubmed:abstractText
A protein allergen extracted from a rough strain of B. melitensis was titrated in sheep sensitized by vaccination with the attenuated B. melitensis strain Rev. I. Single doses of allergen were given per animal by the intradermal or palpebral routes. Doses over a 100-fold range produced delayed hypersensitivity reactions of similar magnitude by both routes. The most suitable method for application in the field was a dose of 50 mug given by the palpebral route (0.5 ml subcutaneously in the upper eyelid) with readings taken 48 hours after inoculation. Sheep vaccinated with H 38 adjuvant vaccine for 6 to 9 months showed positive reaction to the allergic test, whereas non-vaccinated non-infected sheep showed no reactions. No increase in agglutinations titers following allergic test was observed in either Rev. I or H 38 vaccinated sheep.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-4193
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Titration of a brucella protein allergen in sheep sensitized with Brucella melitensis.
pubmed:publicationType
Journal Article