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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-10-18
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pubmed:abstractText |
Amlodipine increases NO levels in coronary vessels and aorta via bradykinin-dependent mechanisms in vitro. We have previously reported that nifedipine increases cardiac NO levels in the ischemic canine hearts, suggesting that nifedipine may also have protective effects against ischemia and reperfusion injury, because the enhancement of NO production limits infarct size. We tested whether nifedipine limits infarct size via NO-dependent mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0300-8428
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pubmed:author |
pubmed-author:AsakuraMM,
pubmed-author:AsanumaHH,
pubmed-author:FunayaHH,
pubmed-author:HoriMM,
pubmed-author:KitakazeMM,
pubmed-author:KuzuyaTT,
pubmed-author:MinaminoTT,
pubmed-author:MoriHH,
pubmed-author:NodeKK,
pubmed-author:SakataYY,
pubmed-author:SanadaSS,
pubmed-author:ShinozakiYY,
pubmed-author:TadaMM,
pubmed-author:TakashimaSS
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pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
497-505
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11605997-Animals,
pubmed-meshheading:11605997-Blood Pressure,
pubmed-meshheading:11605997-Calcium Channel Blockers,
pubmed-meshheading:11605997-Coronary Circulation,
pubmed-meshheading:11605997-Dogs,
pubmed-meshheading:11605997-Endothelium,
pubmed-meshheading:11605997-Enzyme Inhibitors,
pubmed-meshheading:11605997-Heart Rate,
pubmed-meshheading:11605997-Myocardial Infarction,
pubmed-meshheading:11605997-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:11605997-Nifedipine,
pubmed-meshheading:11605997-Nitric Oxide,
pubmed-meshheading:11605997-Peroxidase
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pubmed:year |
2001
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pubmed:articleTitle |
Nifedipine limits infarct size via NO-dependent mechanisms in dogs.
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pubmed:affiliation |
Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita City, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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