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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2001-10-17
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pubmed:abstractText |
Various compounds believed to selectively interact with the 5-HT(2C) receptor have been demonstrated to alter the functioning of ascending dopamine systems. We postulated that this functional interaction may extend to the behavioural effects of drugs of abuse whose rewarding properties are critically dependent upon mesolimbic DA activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/6-chloro-5-methyl-1-((2-(2-methylpyr...,
http://linkedlifedata.com/resource/pubmed/chemical/Aminopyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Ethylamines,
http://linkedlifedata.com/resource/pubmed/chemical/Indoles,
http://linkedlifedata.com/resource/pubmed/chemical/Nicotine,
http://linkedlifedata.com/resource/pubmed/chemical/Nicotinic Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Serotonin, 5-HT2C,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Ro 60-0175,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin Receptor Agonists
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0033-3158
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
157
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11605085-Aminopyridines,
pubmed-meshheading:11605085-Animals,
pubmed-meshheading:11605085-Conditioning, Operant,
pubmed-meshheading:11605085-Dose-Response Relationship, Drug,
pubmed-meshheading:11605085-Ethylamines,
pubmed-meshheading:11605085-Food,
pubmed-meshheading:11605085-Indoles,
pubmed-meshheading:11605085-Injections, Intravenous,
pubmed-meshheading:11605085-Male,
pubmed-meshheading:11605085-Motor Activity,
pubmed-meshheading:11605085-Nicotine,
pubmed-meshheading:11605085-Nicotinic Agonists,
pubmed-meshheading:11605085-Rats,
pubmed-meshheading:11605085-Rats, Sprague-Dawley,
pubmed-meshheading:11605085-Receptor, Serotonin, 5-HT2C,
pubmed-meshheading:11605085-Receptors, Serotonin,
pubmed-meshheading:11605085-Reinforcement (Psychology),
pubmed-meshheading:11605085-Serotonin Antagonists,
pubmed-meshheading:11605085-Serotonin Receptor Agonists
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pubmed:year |
2001
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pubmed:articleTitle |
Activation of 5-HT(2C) receptors reduces the locomotor and rewarding effects of nicotine.
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pubmed:affiliation |
PRBN-B, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
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pubmed:publicationType |
Journal Article
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