rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2001-10-16
|
pubmed:abstractText |
One hundred fifty patients undergoing carotid endarterectomy were randomly assigned to receive intravenous 10% dextran 40 or placebo. Transcranial Doppler monitoring of the ipsilateral middle cerebral artery 0 to 1 hour postoperatively detected embolic signals in 57% of placebo and 42% of dextran patients, with overall embolic signal counts 46% less for dextran (p = 0.052). Two to 3 hours postoperatively, embolic signals were present in 45% of placebo and 27% of dextran patients, with embolic signal counts 64% less for dextran (p = 0.040). We conclude that dextran reduces embolic signals within 3 hours of CEA.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0364-5134
|
pubmed:author |
pubmed-author:AbbottA LAL,
pubmed-author:CameronH MHM,
pubmed-author:ChambersB RBR,
pubmed-author:ChanA TAT,
pubmed-author:DonnanG AGA,
pubmed-author:FellGG,
pubmed-author:HoareM CMC,
pubmed-author:LeviC RCR,
pubmed-author:PeetersAA,
pubmed-author:RobertsA KAK,
pubmed-author:RoyleJ PJP,
pubmed-author:StorkJ LJL
|
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
544-7
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:11601508-Aged,
pubmed-meshheading:11601508-Anticoagulants,
pubmed-meshheading:11601508-Carotid Stenosis,
pubmed-meshheading:11601508-Dextrans,
pubmed-meshheading:11601508-Endarterectomy, Carotid,
pubmed-meshheading:11601508-Female,
pubmed-meshheading:11601508-Humans,
pubmed-meshheading:11601508-Injections, Intravenous,
pubmed-meshheading:11601508-Intracranial Embolism,
pubmed-meshheading:11601508-Male,
pubmed-meshheading:11601508-Middle Aged,
pubmed-meshheading:11601508-Postoperative Complications,
pubmed-meshheading:11601508-Ultrasonography, Doppler, Transcranial
|
pubmed:year |
2001
|
pubmed:articleTitle |
Dextran reduces embolic signals after carotid endarterectomy.
|
pubmed:affiliation |
Department of Neurology, John Hunter Hospital, Newcastle, Australia.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|