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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2001-10-12
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pubmed:abstractText |
2-(Anilinomethyl)imidazolines with 2'-esters or 2'-amides are potent agonists of the cloned human alpha(1)-adrenoceptors in vitro. The size and shape of the ortho substituent can have significant effects on the potency, efficacy, and subtype selectivity of these 2-(anilinomethyl)imidazolines. alpha(1A)-subtype selective agonists have been identified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:BermanJJ,
pubmed-author:BighamE CEC,
pubmed-author:BishopM JMJ,
pubmed-author:GarrisonD TDT,
pubmed-author:GobelM JMJ,
pubmed-author:HodsonS JSJ,
pubmed-author:IrvingP EPE,
pubmed-author:LiacosJ AJA,
pubmed-author:MinickD JDJ,
pubmed-author:NavasFF,
pubmed-author:SaussyD LDLJr,
pubmed-author:SpeakeJ DJD
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2871-4
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
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pubmed:year |
2001
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pubmed:articleTitle |
2-(Anilinomethyl)imidazolines as alpha(1)-adrenoceptor agonists: the identification of alpha(1A) subtype selective 2'-carboxylic acid esters and amides.
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pubmed:affiliation |
GlaxoSmithKline, 5Moore Drive, Research Triangle Park, NC 27709, USA. mjb45288@glaxowellcome.com
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pubmed:publicationType |
Journal Article
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