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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2001-10-12
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pubmed:abstractText |
A series of aromatic, serum-stable, water soluble and nontoxic amino acid phosphoramidate monoesters of 5-fluoro-2'-deoxyuridine (FUdR) and 1-beta-arabinofuranosylcytosine (Ara-C) was shown to inhibit the cellular growth of the human leukemia cell line CCRF-CEM in the presence of human prostatic acid phosphatase (hPAP).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2803-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11597404-Amides,
pubmed-meshheading:11597404-Cell Division,
pubmed-meshheading:11597404-Enzymes,
pubmed-meshheading:11597404-Humans,
pubmed-meshheading:11597404-Leukemia,
pubmed-meshheading:11597404-Nucleosides,
pubmed-meshheading:11597404-Phosphoric Acids,
pubmed-meshheading:11597404-Protein Tyrosine Phosphatases,
pubmed-meshheading:11597404-Substrate Specificity,
pubmed-meshheading:11597404-Tumor Cells, Cultured
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pubmed:year |
2001
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pubmed:articleTitle |
Amino acid phosphoramidate nucleosides: potential ADEPT/GDEPT substrates.
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pubmed:affiliation |
Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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