Linked Life Data

11596052

Source:http://linkedlifedata.com/resource/pubmed/id/11596052

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-10-11
pubmed:abstractText
Based on Fos expression, four areas of the gerbil brain are activated with ejaculation, i.e., the posterodorsal preoptic nucleus (PdPN), the lateral part of the posterodorsal medial amygdala (MeApd), the medial cell group of the sexually dimorphic preoptic area (medial SDA), and the parvicellular part of the subparafascicular thalamus (SPFp). The SPFp and medial SDA also express Fos earlier in the context of mating. To study connections among these areas, we injected one with FluoroGold and assessed the colocalization of FluoroGold and mating-induced Fos in the others. To determine if any of these areas activates the others, we lesioned one unilaterally and measured mating-induced Fos ipsilaterally and contralaterally in the others. Half of the SPFp cells projecting to the medial SDA, PdPN, and MeApd were activated with mating. SPFp lesions also decreased Fos expression in those areas. However, those areas do not project to the SPFp or affect its Fos expression with mating. Projections from the lateral MeApd to the medial SDA and PdPN, and from the medial SDA to the lateral MeApd, were also activated with mating, but lesions in these areas did not affect Fos expression in the others. Because 32-50% of the mating-activated cells in the SPFp participated in each SPFp projection identified, projections may have been identified for all of the mating-activated cells in the SPFp. In contrast, most of the mating-activated cells in the lateral MeApd, PdPN, and medial SDA do not participate in any projection studied, suggesting that they are either interneurons or project elsewhere.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-9967
pubmed:author
pubmed:copyrightInfo
Copyright 2001 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
439
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
248-58
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:11596052-Amygdala, pubmed-meshheading:11596052-Animals, pubmed-meshheading:11596052-Axonal Transport, pubmed-meshheading:11596052-Copulation, pubmed-meshheading:11596052-Denervation, pubmed-meshheading:11596052-Ejaculation, pubmed-meshheading:11596052-Excitatory Amino Acid Agonists, pubmed-meshheading:11596052-Female, pubmed-meshheading:11596052-Fluorescent Dyes, pubmed-meshheading:11596052-Functional Laterality, pubmed-meshheading:11596052-Gerbillinae, pubmed-meshheading:11596052-Immunohistochemistry, pubmed-meshheading:11596052-Male, pubmed-meshheading:11596052-Microinjections, pubmed-meshheading:11596052-Molecular Probes, pubmed-meshheading:11596052-N-Methylaspartate, pubmed-meshheading:11596052-Neural Pathways, pubmed-meshheading:11596052-Neurons, pubmed-meshheading:11596052-Neurotoxins, pubmed-meshheading:11596052-Preoptic Area, pubmed-meshheading:11596052-Prosencephalon, pubmed-meshheading:11596052-Proto-Oncogene Proteins c-fos, pubmed-meshheading:11596052-Stilbamidines, pubmed-meshheading:11596052-Thalamus
pubmed:year
2001
pubmed:articleTitle
Anatomical and functional connections among cell groups in the gerbil brain that are activated with ejaculation.
pubmed:affiliation
Department of Neurobiology and Behavior, University of California, Irvine, California 92697-4550, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.