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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2001-10-11
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pubmed:abstractText |
The p53 tumor suppressor gene plays a central role in cell cycle regulation and induction of apoptosis. We analyzed p53 alterations and their impact on response to chemotherapy and clinical outcome in ovarian cancer patients.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:El-NaggarAA,
pubmed-author:GeeCC,
pubmed-author:JonesL ALA,
pubmed-author:KilianUU,
pubmed-author:KreienbergRR,
pubmed-author:LIUT STS,
pubmed-author:LichteneggerWW,
pubmed-author:MinguillonCC,
pubmed-author:PressM FMF,
pubmed-author:ReichOO,
pubmed-author:RelesAA,
pubmed-author:RunnebaumI BIB,
pubmed-author:SchönbornII,
pubmed-author:SchmiderAA
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2984-97
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11595686-Aged,
pubmed-meshheading:11595686-Antineoplastic Agents,
pubmed-meshheading:11595686-Cisplatin,
pubmed-meshheading:11595686-DNA, Neoplasm,
pubmed-meshheading:11595686-DNA Mutational Analysis,
pubmed-meshheading:11595686-Disease Progression,
pubmed-meshheading:11595686-Drug Resistance, Neoplasm,
pubmed-meshheading:11595686-Female,
pubmed-meshheading:11595686-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11595686-Humans,
pubmed-meshheading:11595686-Infant, Newborn,
pubmed-meshheading:11595686-Middle Aged,
pubmed-meshheading:11595686-Multivariate Analysis,
pubmed-meshheading:11595686-Mutation,
pubmed-meshheading:11595686-Neoplasm Staging,
pubmed-meshheading:11595686-Ovarian Neoplasms,
pubmed-meshheading:11595686-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:11595686-Prognosis,
pubmed-meshheading:11595686-Survival Analysis,
pubmed-meshheading:11595686-Time Factors,
pubmed-meshheading:11595686-Tumor Suppressor Protein p53
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pubmed:year |
2001
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pubmed:articleTitle |
Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer.
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pubmed:affiliation |
Department of Pathology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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