Linked Life Data

1158660

Source:http://linkedlifedata.com/resource/pubmed/id/1158660

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1975-12-5
pubmed:abstractText
Simultaneous determinations of cerebral blood flow, measured by 85Kr clearance, and of intracranial pressure, measured in the cisterna magna, were made in anesthetized normocapnic and hypercapnic vagotomized cats. All animals were tested at their normal arterial pressure and at elevated arterial pressure induced by angiotensin infusion. Autoregulatory responses of cerebral blood vessels to the elevation of blood pressure were quantitatively characterized by a pressure-flow function. In 10 of 12 animals, hypercapnia interfered with the autoregulatory responses of the cerebral vasculature. Analysis of the simultaneous behavior of intracranial pressure and cerebral vascular resistance did not indicate that changes in intracranial pressure affected the autoregulatory responses. The results of this study support the view that CO2 interferes with the basic reaction of vascular smooth muscle to contract after distension by increased transmural pressure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-2180
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
469-75
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Autoregulatory responses of cerebral blood vessels in hypercapnia.
pubmed:publicationType
Journal Article