Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-10-3
pubmed:abstractText
Two cases of ductal cancers of the breast of no special type with a prominent rhabdoid component are presented. The mastectomy specimens showed the tumors to be composed of cells with a characteristic rhabdoid phenotype: Large cells with eccentric nuclei containing large inclusion like nucleoli and abundant eosinophilic cytoplasm. Immunohistochemistry showed typical immunoreactivity with cytoplasmic dot-like accentuation for epithelial markers as well as vimentin. In case 1, although excision margins were clear, tumor recurrence, composed mainly of rhabdoid cells, occurred within 7 months, and the patient died 2 months later. The second case, unfortunately, was lost to follow-up. This report is the second documenting the occurrence of rhabdoid cells in breast cancer. In keeping with other epithelial malignancies that contain rhabdoid cells, aggressive biological behavior is noted. Int J Surg Pathol 9(3):237-239, 2001
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1066-8969
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Infiltrating ductal carcinoma of the breast with rhabdoid phenotype.
pubmed:affiliation
Department of Pathology, Nelson R. Mandela School of Medicine, University of Natal, Durban, South Africa.
pubmed:publicationType
Journal Article, Case Reports