Linked Life Data

11581334

Source:http://linkedlifedata.com/resource/pubmed/id/11581334

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 18
pubmed:dateCreated
2001-10-2
pubmed:abstractText
Human endurance performance is often evaluated on the basis of the maximal rate of oxygen uptake during exercise (V(O(2)max)). Methods for overcoming limits to V(O(2)max) are touted as means for increasing athletic endurance performance. Here, we argue that the respiratory system is well designed for delivering O(2) to meet O(2) demands and that no single factor is rate-determining for O(2) uptake. We show that V(O(2)max) can vary 5000-fold among mammals, while any limitation to O(2) delivery by a single component of the respiratory system affects V(O(2)max) by 10% or less. Attempts to increase O(2) delivery by enhancing one step in the respiratory system are shown to have little effect. Blood doping, hyperoxia and O(2) supplementation of high-altitude natives all raise O(2) availability substantially to the working muscles, but these treatments increase V(O(2)max) only minimally. Finally, we argue that O(2) uptake is only one of a number of properties important to human aerobic performance.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-0949
pubmed:author
pubmed:issnType
Print
pubmed:volume
204
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3195-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Human aerobic performance: too much ado about limits to V(O(2)).
pubmed:affiliation
Physiology and Functional Morphology Group, Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011-5640, USA. Stan.Lindstedt@nau.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review