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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2001-9-28
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pubmed:abstractText |
Reduced body temperature is a common companion to trauma/haemorrhage. Several clinical studies have identified hypothermia as an independent risk variable predisposing to increased morbidity and mortality. At the same time it is known that most enzymatic reactions are downregulated at temperatures below 37 degrees C. Theoretically this should restrain the inflammatory response and protect the host from remote organ injury. The study was performed to test this hypothesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0001-5172
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
994-1001
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11576051-Animals,
pubmed-meshheading:11576051-Hemodynamics,
pubmed-meshheading:11576051-Hypothalamo-Hypophyseal System,
pubmed-meshheading:11576051-Hypothermia, Induced,
pubmed-meshheading:11576051-Inflammation,
pubmed-meshheading:11576051-Interleukin-10,
pubmed-meshheading:11576051-Interleukin-6,
pubmed-meshheading:11576051-Luminescent Measurements,
pubmed-meshheading:11576051-Male,
pubmed-meshheading:11576051-Pituitary-Adrenal System,
pubmed-meshheading:11576051-Rats,
pubmed-meshheading:11576051-Rats, Sprague-Dawley,
pubmed-meshheading:11576051-Shock, Hemorrhagic,
pubmed-meshheading:11576051-Tumor Necrosis Factor-alpha
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pubmed:year |
2001
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pubmed:articleTitle |
Moderate hypothermia blunts the inflammatory response and reduces organ injury after acute haemorrhage.
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pubmed:affiliation |
Norwegian Defence Research Establishment, Division of Protection and Material, Kjeller, Norway. yngvar.gundersen@ffi.no
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pubmed:publicationType |
Journal Article
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