Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2001-9-28
pubmed:abstractText
A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC(50) values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0163-3864
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1238-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11575966-Animals, pubmed-meshheading:11575966-Antioxidants, pubmed-meshheading:11575966-Brain, pubmed-meshheading:11575966-Chromatography, High Pressure Liquid, pubmed-meshheading:11575966-Coumarins, pubmed-meshheading:11575966-Dioxanes, pubmed-meshheading:11575966-Inhibitory Concentration 50, pubmed-meshheading:11575966-Korea, pubmed-meshheading:11575966-Lignans, pubmed-meshheading:11575966-Lipid Peroxidation, pubmed-meshheading:11575966-Magnetic Resonance Spectroscopy, pubmed-meshheading:11575966-Malvaceae, pubmed-meshheading:11575966-Mice, pubmed-meshheading:11575966-Microsomes, Liver, pubmed-meshheading:11575966-Molecular Structure, pubmed-meshheading:11575966-Monoamine Oxidase Inhibitors, pubmed-meshheading:11575966-Plant Roots, pubmed-meshheading:11575966-Plants, Medicinal, pubmed-meshheading:11575966-Rats, pubmed-meshheading:11575966-Scopoletin, pubmed-meshheading:11575966-Spectrophotometry, Infrared, pubmed-meshheading:11575966-Spectrophotometry, Ultraviolet, pubmed-meshheading:11575966-Structure-Activity Relationship, pubmed-meshheading:11575966-Vitamin E
pubmed:year
2001
pubmed:articleTitle
Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus.
pubmed:affiliation
Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, Taejon 305-600, Korea.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro