Linked Life Data

11573658

Source:http://linkedlifedata.com/resource/pubmed/id/11573658

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-9-27
pubmed:abstractText
Doubt remains about the conditions under which learning persists despite anaesthesia. This study investigated the relative importance of dose of anaesthetic and stimulation for learning during propofol infusion before surgery. Thirty-six patients were randomly assigned to three groups. Group 1 received two word lists (category examples and nonsense words) during infusion of propofol to a target concentration of 2 microg ml(-1). Groups 2 and 3 received the word lists during infusion of propofol 5 microg ml(-1). Group 2 received nonsense words before tracheal intubation and category examples during intubation; Group 3 heard category examples before and nonsense words during intubation. Bispectral index was recorded as a measure of depth of sedation/anaesthesia. We assessed explicit memory on recovery using a structured interview and a recognition test. We assessed implicit memory using a category generation test and a preference rating task. To establish baseline, a control group of 12 patients completed the category generation test without receiving the category examples during anaesthesia. Overall, there was no evidence for learning during propofol infusion, though the category generation task showed a trend towards more implicit memory for words presented during intubation than during anaesthesia. We conclude that learning does not occur during anaesthesia without surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-95
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Comparing the effects of stimulation and propofol infusion rate on implicit and explicit memory formation.
pubmed:affiliation
Department of Psychology, University of Sheffield, UK.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial