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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2001-9-25
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pubmed:abstractText |
Arterial stiffening with increased pulse pressure is a leading risk factor for cardiovascular disease in the elderly. We tested whether ALT-711, a novel nonenzymatic breaker of advanced glycation end-product crosslinks, selectively improves arterial compliance and lowers pulse pressure in older individuals with vascular stiffening.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
25
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1464-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11571237-Aged,
pubmed-meshheading:11571237-Arteries,
pubmed-meshheading:11571237-Blood Pressure,
pubmed-meshheading:11571237-Cardiac Output,
pubmed-meshheading:11571237-Compliance,
pubmed-meshheading:11571237-Double-Blind Method,
pubmed-meshheading:11571237-Drug Tolerance,
pubmed-meshheading:11571237-Elasticity,
pubmed-meshheading:11571237-Female,
pubmed-meshheading:11571237-Forecasting,
pubmed-meshheading:11571237-Glycosylation End Products, Advanced,
pubmed-meshheading:11571237-Humans,
pubmed-meshheading:11571237-Male,
pubmed-meshheading:11571237-Middle Aged,
pubmed-meshheading:11571237-Thiazoles
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pubmed:year |
2001
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pubmed:articleTitle |
Improved arterial compliance by a novel advanced glycation end-product crosslink breaker.
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pubmed:affiliation |
Division of Cardiology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. dkass@bme.jhu.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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