rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
Pt 10
|
pubmed:dateCreated |
2001-9-21
|
pubmed:abstractText |
The molecular-replacement method has been extended to locate molecules and their fragments in an electron-density map. The approach is based on a new spherically averaged phased translation function. The position of the centre of mass of a search model is found prior to determination of its orientation. The orientation is subsequently found by a phased rotation function. The technique also allows superposition of distantly related macromolecules. The method has been implemented in a computer program MOLREP and successfully tested using experimental data sets.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chitinase,
http://linkedlifedata.com/resource/pubmed/chemical/Esterases,
http://linkedlifedata.com/resource/pubmed/chemical/Muramidase,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Purine-Nucleoside Phosphorylase,
http://linkedlifedata.com/resource/pubmed/chemical/Pyroglutamyl-Peptidase I,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Transfer, Phe,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Transfer, Ser,
http://linkedlifedata.com/resource/pubmed/chemical/hevamine
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0907-4449
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
57
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1451-6
|
pubmed:dateRevised |
2007-7-24
|
pubmed:meshHeading |
pubmed-meshheading:11567159-Chitinase,
pubmed-meshheading:11567159-Crystallography, X-Ray,
pubmed-meshheading:11567159-Esterases,
pubmed-meshheading:11567159-Models, Molecular,
pubmed-meshheading:11567159-Muramidase,
pubmed-meshheading:11567159-Plant Proteins,
pubmed-meshheading:11567159-Proteins,
pubmed-meshheading:11567159-Purine-Nucleoside Phosphorylase,
pubmed-meshheading:11567159-Pyroglutamyl-Peptidase I,
pubmed-meshheading:11567159-RNA, Transfer, Phe,
pubmed-meshheading:11567159-RNA, Transfer, Ser,
pubmed-meshheading:11567159-Software
|
pubmed:year |
2001
|
pubmed:articleTitle |
Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps.
|
pubmed:affiliation |
Department of Chemistry, University of York, Heslington, York YO1 5DD, England. alexei@ysbl.york.ac.uk
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|