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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2001-9-20
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pubmed:abstractText |
Infusion of insulin produces sympathoexcitation, nitric oxide (NO) generation and NO-mediated vasodilation. Because central nervous system NO may inhibit sympathetic outflow, the present study was designed to determine whether NO synthase blockade would enhance insulin-mediated sympathetic activation. We additionally aimed to determine whether augmented sympathoexcitation and reduced NO-mediated vasodilation, during combined NO synthase blockade and hyperinsulinemia, would result in a blood pressure increase.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0263-6352
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1625-31
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11564983-Animals,
pubmed-meshheading:11564983-Drug Combinations,
pubmed-meshheading:11564983-Enzyme Inhibitors,
pubmed-meshheading:11564983-Heart Rate,
pubmed-meshheading:11564983-Insulin,
pubmed-meshheading:11564983-Lumbosacral Region,
pubmed-meshheading:11564983-Male,
pubmed-meshheading:11564983-Nitric Oxide Synthase,
pubmed-meshheading:11564983-Rats,
pubmed-meshheading:11564983-Rats, Wistar,
pubmed-meshheading:11564983-Sympathetic Nervous System,
pubmed-meshheading:11564983-omega-N-Methylarginine
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pubmed:year |
2001
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pubmed:articleTitle |
Inhibition of nitric oxide synthesis attenuates insulin-mediated sympathetic activation in rats.
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pubmed:affiliation |
Department of Biological Sciences, Lehman College, Bronx, New York 10468, USA. martinmu@alpha.lehman.cuny.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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