Source:http://linkedlifedata.com/resource/pubmed/id/11564442
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2001-9-20
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pubmed:abstractText |
In normal mice, a subpopulation of CD4 T cells constitutively express CD25. These cells behave as regulatory T cells in autoimmune and inflammatory reactions, in tolerance to superantigens, and in peripheral T-cell homeostasis. They are unable to produce interleukin (IL)-2, and are dependent on IL-2 for growth in vitro and in vivo. CD4 CD25(+) T cells spontaneously secrete IL-10, which is involved in some of their regulatory functions. They are resistant to apoptosis, but can be tolerized by anergy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1286-4579
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
937-45
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:11564442-Animals,
pubmed-meshheading:11564442-Autoimmune Diseases,
pubmed-meshheading:11564442-CD4-Positive T-Lymphocytes,
pubmed-meshheading:11564442-Clonal Anergy,
pubmed-meshheading:11564442-Homeostasis,
pubmed-meshheading:11564442-Immune Tolerance,
pubmed-meshheading:11564442-Inflammation,
pubmed-meshheading:11564442-Mice,
pubmed-meshheading:11564442-Mice, Inbred BALB C,
pubmed-meshheading:11564442-Receptors, Interleukin-2,
pubmed-meshheading:11564442-T-Lymphocyte Subsets
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pubmed:year |
2001
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pubmed:articleTitle |
Natural regulatory CD4 T cells expressing CD25.
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pubmed:affiliation |
Inserm U.345, Institut Necker, 156, rue de Vaugirard, 75730 Paris cedex 15, France. papernik@necker.fr
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pubmed:publicationType |
Journal Article,
Review
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