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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1975-11-5
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pubmed:abstractText |
1. The biliary excretion of phenolphthalein di[35S]sulphate was studied in rats. 2. The conjugate was administered by continuous infusion at rates of 3, 4.5, 6, 9 and 12 mug/min, and kinetic analysis of the rate of biliary excretion was consistent with a two-compartment open-model system. 3. The results obtained after single injections of the ester were also consistent with the model. 4. An essential feature of the model is the presence of a compartment into which the ester may pass as an alternative to direct excretion via the bile. 5. It is suggested that such a compartment may be located within the liver.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0264-6021
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
303-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:1156406-Animals,
pubmed-meshheading:1156406-Anions,
pubmed-meshheading:1156406-Bile,
pubmed-meshheading:1156406-Biliary Tract,
pubmed-meshheading:1156406-Infusions, Parenteral,
pubmed-meshheading:1156406-Kinetics,
pubmed-meshheading:1156406-Male,
pubmed-meshheading:1156406-Models, Biological,
pubmed-meshheading:1156406-Phenolphthaleins,
pubmed-meshheading:1156406-Rats
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pubmed:year |
1975
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pubmed:articleTitle |
A model system for investigating the biliary excretion of an anion in the rat.
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pubmed:publicationType |
Journal Article
|